Is the NIFTY test accurate for twins?

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I am from India and i am expecting twins so can i get NIFTY test done for twins as well. Currently i am 17 weeks approx pregnant


The NIFTY Test is a screening test for diagnosing fetal down’s syndrome with 99% accuracy. With respect to your case, we recommend an Amniocentesis Test rather than a NIFTY Test for the following reasons:

  1. In case of a twin pregnancy, a positive test result CAN NOT point out which fetus has chromosomal abnormalities.
  2. Even though the NIFTY test is a highly effective screening test, it is not used for making a diagnosis. If the test results indicate an abnormality, an amniocentesis is recommended to confirm the result. According to the American Pregnancy Association, it is usually performed between 14 and 20 weeks. Please note that it takes about three weeks for the test results to come through. It is important to consider what the test result would mean to you, and how it might impact your decision to carry the child to full term.
  3. An amniocentesis is usually performed around week 16 so it is suitable for your gestational age. However some mothers fear amniocentesis since it is recognized as an invasive diagnostic test that carries potential risks. You can consult with your health care provider or find out more information from the American Pregnancy Association in this discussion about procedures, risks and side effects to the mother or baby:

Making a decision about any form of prenatal testing during pregnancy is difficult but important. You can consult with your healthcare provider or let us know if you have any further questions.

Boonsaeng Wutthiphan M.D.
Samitivej Sukhumvit Hospital

Expecting Expats is the online resource for parents in and around Thailand.

We provide lifestyle and medical content to our visitors, with new content posted daily. Our lifestyle contributors are themselves expat moms who share their experiences and lessons learned through blog articles. We also provide medical content from our partner doctors at Samitivej Hospital in Bangkok, Thailand. Articles of interest span from before pregnancy through the toddler years and cover medical, behavioral and cognitive issues.

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  1. Sequin  /  July 23, 2014, 3:25 pm Reply

    So if you are pregnant with twins and have a NIFTY test that is positive does it mean there is likely no problem. But you are saying that, if the NIFTY test finds a chromosomal issue, that it is impossible to know which twin/s have the chromosomal issue (hence only
    Amnio can tell that?). Please clarify. Thanks!

    • admin  /  July 31, 2014, 2:55 pm Reply

      Hello and thank you again for your question.

      We have received the following reply from Dr. Boonsaeng Wutthiphan M.D. at Samitivej Sukhumvit Hospital’s Women’s Health Center. If you have any additional questions, please let us know:

      The NIFTY test is a screening test, it is not used for making a diagnosis. If the test result shows a high risk, an amniocentesis is recommended to confirm the result for both single and twin pregnancy. As mentioned in the above answer, in case of a twin pregnancy, a positive test result CAN NOT point out which fetus has chromosomal abnormalities, as each fetus has its own risk of a genetic abnormality. With an Amniocentesis your doctor can collect a sample from each baby.

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